A study which combines mathematical modelling and experimental measurements to determine the effects of redox charge on glycolytic flux
SEEK ID: https://demo.fairdomhub.org/studies/6
Glycolitic Flux in Lactococcus lactis
Projects: SysMO DB
Study position:
Experimentalists: Ana Rute Neves, Rita Ventura, Nahla Mansour, Claire Shearman, Michael J. Gasson, Christopher Maycock, Ana Ramos, and Helena Santos
Export PNG
Views: 6963
Created: 8th Aug 2011 at 13:50
Last updated: 4th Nov 2011 at 10:06
This item has not yet been tagged.
Related items
- People (1)
- Programmes (1)
- Projects (1)
- Investigations (1)
- Assays (2)
- Data files (1)
- Models (1)
- Publications (1)
Expertise: Biochemistry, Bioinformatics, Data Management
Tools: Data Management, Transcriptomics, Databases, Workflows, Web services, Taverna, Ontologies
I am a Research Fellow at the University of Manchester, working in Bioinformatics and Computer Science. I am also a guest researcher at the Vrije Universiteit.My research interests include scientific workflows, semantic discovery, and applying ontology technologies to biological data
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO is to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB
Web page: http://sysmo.net/
The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:
- facilitates and maximises the potential for data exchange between SysMO research groups;
- maximises the ‘shelf life’ and ...
Programme: SysMO
Public web page: http://www.sysmo-db.org/
Organisms: Saccharomyces cerevisiae, Lactic Acid Bacteria
An investigation into the control mechanisms of glycolytic flux in Lactococcus lactis.
This investigation represents the data and models published by Hoefnagel et al in JWS Online and in M.H.N. Hoefnagel, J. Hugenholtz and J.L. SnoepMol. Biol. Reports 29, 157-161 (2002)
Submitter: Katy Wolstencroft
Studies: The effects of Redox Charge on Glycolytic Flux
Assays: NAD+ and NADH Kinetics, using 13C NMR, Time dependent responses of glycolytic intermediates in a detailed glyco...
Snapshots: No snapshots
Submitter: Katy Wolstencroft
Assay type: Glucose Pulse
Technology type: NMR
Investigation: Glycolitic Flux in Lactococcus lactis
Detailed glycolytic model in Lactococcus lactis
Submitter: Katy Wolstencroft
Biological problem addressed: Metabolic Network
Investigation: Glycolitic Flux in Lactococcus lactis
Organisms: Lactococcus lactis
Models: Lactococcus lactis glycolysis
SOPs: No SOPs
Data files: Neves_timeSeries
Snapshots: No snapshots
Creator: Jacky Snoep
Submitter: Katy Wolstencroft
Investigations: Glycolitic Flux in Lactococcus lactis
Detailed kinetic model for glycolysis of L. lactis. The model is basically the same model as that published by Hoefnagel et al 2002 (Mol. Biol. Reports 29, 157-161). The change made to the model is to make external glucose a variable such that a glucose pulse can be simulated.
Creators: Jacky Snoep, Ana Rute Neves
Submitter: Katy Wolstencroft
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Organism: Lactococcus lactis
Investigations: Glycolitic Flux in Lactococcus lactis
Abstract (Expand)
Authors: Ana Rute Neves, Rita Ventura, Nahla Mansour, Claire Shearman, Michael J Gasson, Christopher Maycock, Ana Ramos, Helena Santos
Date Published: 13th May 2002
Publication Type: Not specified
PubMed ID: 12011086
Citation: